Sedating antihistamine drugs, the Use of Antihistamines
Second generation antihistamines were developed in the s and are much less sedating than first-generation antihistamines. Doctors frequently recommend antihistamines over common prescription sleep aids when the patient has insomnia because of drug and alcohol withdrawal. The main use for niaprazine is its intense sedative effect as opposed to its antihistamine effects. Some antihistamines can cross the blood-brain barrier and get to the relevant receptors. And like other hypnotics, dating ideas in dallas the long-term effectiveness of antihistamines has not been demonstrated in a manner that would satisfy scientists.
Types of Antihistamines
What are antihistamines used for?
Common antihistamines available in the U. People build up tolerance to them over time and when they stop taking them experience rebound insomnia. For people who need to get to sleep, however, the drowsiness is the main benefit of antihistamines.
First-generation antihistamines were developed more than seventy years ago and are still in widespread use today. Profound drowsiness is a very common side effect, as is dizziness, difficulty concentrating, and urinary retention. The ones you see in over-the-counter sleep aids are usually diphenhydramine and hydroxyzine.
Clemastine is indicated for the treatment of allergy symptoms, including rhinitis and pruritus itching or hives. Hydroxyzine is used for allergies and to suppress nausea.
Patient response and occurrence of adverse drug reactions vary greatly between classes and between agents within classes. Niaprazine was invented in France, and is used mainly in the European Union.
What are Antihistamines?
However, some feel the trade-off to stop insomnia is worth it. There are plenty at your local drug store. Some people want an analgesic mixed in with their antihistimine, but if you do not, look for antihistimine sleep aids with no pain reliever. They also act on muscarinic, alpha-adrenergic, and serotonin receptors. It is indicated for the treatment of hay fever, asthma, urticaria, and rhinitis, and is a mild sedative.
If you take a medicine like this to help you sleep, be aware of the pain reliever in the pill. In addition to effects on serotonin and norepinephrine, doxepin appears to have anti-histamine properties. Under the new name Silenor it is being marketed explicitly for sleep disorders.
They do, however, have the potential for negative effects if taken with other drugs, so let your doctor know if you are taking more than one medication. Cyproheptadine belongs to the family of drugs called antihistamines. These, like diphenhydramine, are useful as sedatives. The regulatory authorities have decided they are safe enough that responsible adults can use them unsupervised. It is usually not appropriate for use just as a sleep aid.
Be sure to run this idea by your doctor, though, because there is a risk and you should avoid mixing sleeping pills and other substances. Vertigo and daytime sedation are frequently encountered with the use of this drug. The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. This drug, under the brand name Sinequan, was prescribed off-label for insomnia in the past.
Although it is a sedative antihistamine, its effects are less intense than many other drugs of this nature. Types of Antihistamines Doxylamine can be used by itself as a sleep aid or combined with other drugs for cold and allergy relief usually in a night-time formula. These are usually not prescription drugs and can be purchased at retailers over-the-counter.
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